EN
cn 
100g/bag; 500g/bag; 1kg/bag
Address
中国.山东聊城开发区创业大厦
Afoxolaner for dogs and afoxolaner for cats is used to treat and control flea and tick infestations in dogs and cats. After being ingested by a pet, afoxolaner is distributed throughout the pet’s body. When fleas or ticks bite the pet, they are exposed to the drug and killed during their blood meal. Gihi Chemicals also has afoxolaner for cats. Sometimes afoxolaner is used for the treatment of sarcoptic mange or demodectic mange. When afoxolaner is prescribed for the treatment of mange, it is referred to as "extra label" or "off label" use.
4-[5-[3-Chloro-5-(trifluoromethyl)phenyl]-4, 5-dihydro-5-(trifluoromethyl)-3-isoxazolyl]-N-[2-oxo-2-[(2, 2, 2-trifluoroethyl)amino]ethyl]-1-naphthalenecarboxamide; Afoxolaner; 1-NaChemicalbookphthalenecarboxamide, 4-[5-[3-chloro-5-(trifluoromethyl)phenyl]-4, 5-dihydro-5-(trifluoromethyl)-3-isoxazolyl]-N-[2-oxo-2-[(2, 2, 2-trifluoroethyl)amino]ethyl]-; Afoxolanerfandachem
CAS No.: 1093861-60-9
EC No.: 832-051-7
MF: C26H17ClF9N3O3
MW: 62.587
Item | Specification | Results |
Appearance | White To Off-white Crystalline Powder | Complies |
Identification | HPLC: HPLC Retention Time Confirms To Standard | Complies |
Melting Point | 148-155℃ | 148-150℃ |
Water | ≤0.1% | 0.07% |
Residue Solvents | Dichloromethane≤600ppm | N.D. |
Isopropyl Acetate≤5000ppm | N.D. | |
Isopropanol≤890ppm | 2ppm | |
N, N-Dimethylformamide≤880ppm | N.D. | |
Methanol≤3000ppm | N.D. | |
Tetrahydrofuran≤720ppm | N.D. | |
Triethylamine≤5000ppm | N.D. | |
Residue On Ignition | ≤0.1% | 0.02% |
Related Substances | Impurity D≤0.15% | N.D. |
Impurity F≤0.15% | 0.08% | |
Individual Unknown Impurity≤0.10% | 0.06% | |
Total Impurities≤1.00% | 0.38% | |
Assay(Anhydrous Substance) | 98.0%~102.0% | 99.10% |
100g/bag; 500g/bag; 1kg/bag
Store in a cool, dry and ventilated place.
2 - 8 °C
Pharmaceutical intermediates
When fleas or ticks bite the dog, they are exposed to the drug and killed during their blood meal.
When afoxolaner is prescribed for the treatment of mange, it is referred to as 'extra label' or 'off label' use.
