Isotretinoin

Tretinoin is the acid form of vitamin A and is also known as all-trans retinoic acid or ATRA. It is a drug commonly used to treat acne vulgaris and keratosis pilaris. It is available as a cream or gel It is also used to treat acute promyelocytic leukemia.

Its success in treating acute promyelocytic leukemia was a major breakthrough in the treatment of this type of leukemia. It works in APL because the majority of cases involve a chromosomal translocation of chromosomes 15 and 17, which causes genetic fusion of the retinoic acid receptor gene to the promyelocytic leukemia gene.

Synonym

TretinoinImpurity1（TretinoinEPImpurityA）; AntiAcnePowerfulIsotretinoinPowderIsotretinoinPharmaceuticalRawMaterials; IsotretinoinCapsules; Isotretinoin-D5/13-cChemicalbookis-Retinoicacid-D5; Roaccutan; (2Z,4E,6E,8E)-3,7-diMethyl-9-(2,6,6-triMethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenoicacid; ISOTRETINON; AdifferentdiMensionacid

• CAS No.: 4759-48-2

• EC No.: 225-296-0

• MF: C20H28O2

• MW: 300.44